Fourteen (20.0%) patients had antiphospholipid antibodies (APL-Abs; 7 patients with lupus anticoagulant, 6 patients with aCLs, and 1 patient with both APL-Abs; aCL-IgM mean activity, 14.7 MPLU/ml; range, 7.6–34.1 MPLU/ml; aCL-IgG mean activity, 13.8 GPLU/ml; range, 12.7–14.8 GPLU/ml). The gene discussed is CD40LG; the disease is acrocallosal syndrome.