In the subset of tularemia patients in whom an elevated CD3+/CD4–/CD8– T-cell percentage was detected while serology was still negative (58.6%, 34/58), the median delay from rise of CD3+/CD4–/CD8– T cells to positive serologic test result was 14 (95% CI 8–22) days (Table 3). Here, CD8A is linked to tularemia.