In combination, TAp73 mRNA expression levels and the seroreactivity to p73, and ΔNp73α, and ΔNp73β did not improve the performance of the seroreactivity to detect CRC and premalignant individuals, showing an AUC of 71.6% and a specificity and sensitivity of 81.0% and 59.4% (Fig. 4c). The gene discussed is TP73; the disease is colorectal carcinoma.