Furthermore, mathematical scoring systems combining serum biomarkers such as aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio (AAR), AST-to-platelet ratio index (APRI), and fibrosis-4 (FIB-4) score have been developed to stage CLD and determine disease severity7–9. Here, GPT is linked to congenital secretory chloride diarrhea 1.