Among the 12 putatively casual CpGs for CHD and MI, we found five CpGs that were positively associated with CHD/MI risk (e.g., cg24267699 in ABO, OR = 2.89, PMR = 1.34E−6), and seven CpGs inversely associated with CHD/MI risk (e.g., cg09803321 in NT5C2, OR = 0.28, PMR = 3.75E−15). The gene discussed is ABO; the disease is coronary artery disorder.