Another interesting interaction observed in our DNLC network (Figure 6A) was between an NENF protein involved in neuronal differentiation and survival (Kimura et al., 2008) and a PD-causing protein (DJ-1, the product of PARK7 gene) implicated in the maintenance of mt homeostasis (Ottolini et al., 2013). This evidence concerns the gene PARK7 and Parkinson disease.