COL1A1 and scoliosis: After multiple testing correction a common variant of COL1A1 gene, rs2075557, was associated with scoliosis (OR = 0.2533, adjusted p-value = 0.04), moreover other 4 SNPs in COL1A1 were also associated with scoliosis, although at marginal level: rs2696247 (OR = 0.266, adjusted p-value = 0.07), rs2075554 (OR = 0.267, adjusted p-value = 0.102), rs2277632 (OR = 0.295, adjusted p-value = 0.121), rs2586494 (OR = 0.305, adjusted p-value = 0.141).