FGFR3 and cancer: To date, there are some strategies to inhibit FGFR3 functions, such as small molecular inhibitor, small interfering RNA (siRNA), monoclonal antibody and single chain variable fragment (ScFv), etc. Several small molecular inhibitors against FGFR3 tyrosine kinase have shown cytotoxic responses and anti-cancer effects in the bladder cancer and MM (Saichaemchan et al. 2016).