SNCA and multiple system atrophy: As in MSA the oligodendrocytes are the cells most frequently affected by α-synuclein aggregation, it is interesting to note that our findings point to several genes that are mainly expressed in oligodendrocytes, such as HIP1 and MOBP, while SNCA is expressed in neurons and oligodendrocytes in similar proportions, and LMAN2 is more highly expressed in astrocytes and microglia (as seen in single cell RNAseq data, https://www.brainrnaseq.org/).