Furthermore, while in acute inflammation the C/EBPα interacts with the p50 NF-κB subunit to stimulate neutrophil production [47], C/EBPβ is a critical regulator of altered myelopoiesis in cancer bearers, contributing to the accumulation of MDSC and to the creation of an immunosuppressive environment [48]. The gene discussed is NFKB1; the disease is cancer.