Some promising therapies addressing novel targets, such as incretin-based therapies glucagon-like peptide-1 (GLP-1) receptor antagonists and dipeptidyl peptidase-4 (DPP-4) inhibitors, might improve albuminuria in type 2 diabetes, while effects on clinically relevant kidney outcomeshile effects on clinically relevant kidney outcomes are still under evaluation [7]. This evidence concerns the gene DPP4 and type 2 diabetes mellitus.