Danhong injection (DHI), a certificated Chinese medical product made from radix salviae miltiorrhizae and flos carthami, could induce the expression of IRS1, FGF21, and peroxisome proliferator-activated receptor γ (PPARγ) in tissues and circulation, which can make contribution to increasing insulin sensitivity and inhibiting the development of DKD [29]. This evidence concerns the gene INS and diabetic kidney disease.