Oleksyk et al. [33] reported that the E1 haplotype of the MYH9 gene region, prominent in sub-Saharan Africa, is probably involved in the increased risk of developing CKD by increasing glomerulosclerosis and proteinuria through activation of nephritis by the deregulation of podocyte function and not by immunological mechanisms. This evidence concerns the gene MYH9 and glomerulosclerosis.