The AST/ALT ratio of 1 : 2 or more was the predictor of poor prognosis of disease progression (HR 1.37, 95% CI 1.00–1.88, P = 0.048), overall mortality (HR 1.56, 95% CI 1.07–2.27, P = 0.021), and cancer-specific mortality (HR 1.97, 95% CI 1.25–3.12, P = 0.004) [22]. Here, GPT is linked to cancer.