Interestingly, a group of myosin related genes were also regulated by Talazoparib treatment, including Myl1, Myh1, Myh2, Myh4, Mybpc2 and Mylpf. Myosins play critical roles in various processes during tumor development, including cell adhesion, migration, and suppression of apoptosis. The gene discussed is MYH4; the disease is neoplasm.