EGFR and non-small cell lung carcinoma: Collectively, the data demonstrate that the combination treatment of ATV and Gefitinib demonstrate superior tumor growth suppression and concomitant reduced cellular cholesterol levels, over ATV or Gefitinib alone, in induced (PC-9GR and H1975) but not in native EGFR-TKI resistant (H1703) NSCLC and NL20 cells.