LGALS3 and acute kidney injury: Consistently, cellular make-up of the kidneys revealed significantly increased total number of IFN-γ and IL-17 producing neutrophils (Figure 8I-J, p<0.05) and CD4+ T cells (Figure 8K-L, p<0.01 for Th1 and p<0.05 for Th17 cells) in the CDDP-injured kidneys of WTGal-3-/-DCsPam3CSK4 mice, indicating that transfer of Gal-3-/-DCsPam3CSK4 aggravated AKI in CDDP-treated WT recipients by enhancing IFN-γ and IL-17-driven inflammation.