LGALS3 and acute kidney injury: On the contrary, single intravenous injection of Gal-3-/-DCsPam3CSK4 notably aggravated CDDP-induced AKI in WT recipients (WTGal-3-/-DCsPam3CSK4), as evidenced by significantly increased serum levels of urea (Figure 8A, p<0.01), creatinine (Figure 8B, p<0.05), histological score (Figure 8C, p<0.05) and massive destruction of proximal tubules (Figure 8D).