To explore whether TCF12 can also increase CXCL12 expression and secretion in HCC cells, we first detected CXCL12 mRNA expression in 24 HCC cell lines using RT-qPCR and found that CXCL12 could be detected in 12 HCC cell lines, with TCF12 mRNA highly expressed in most HCC cells (Figure S3F). The gene discussed is CXCL12; the disease is hepatocellular carcinoma.