Interestingly, TCGA RNA sequencing data also identified an association of higher MT-CO3 expression levels with increased overall survival in four cancer types, including adrenocortical carcinoma (ACC), kidney chromophobe (KICH), low-grade glioma (LGG), and pancreatic adenocarcinoma (PAAD) (Figure 6E). This evidence concerns the gene MT-CO3 and cancer.