CD40LG and neoplasm: Furthermore, since the adenoviral vector has been armed with human CD40 ligand (CD40L), we have performed quantification measurements of this exogenous protein specifically produced by the virus: the analysis provided consistent results compared with the qPCR data: the highest concentration of the CD40L was found in tumour tissues (Figure S3C-D) 5-fold higher compared to the one found in serum and liver.