ABCG2 and infection: In addition, Du and Jin19 and Chen et al. 17 found GE changes in ABC transporters after WSSV infection in red swamp crayfish gills and whiteleg shrimp hepatopancreas: interestingly, while in whiteleg shrimp hepatopancreas ABC transporters were down-regulated, in red swamp crayfish gills ABC were upregulated, suggesting that an important difference exists between these two tissues.