Albumin-to-fibrinogen ratio (AFR), which takes both Alb and Fib into account, has been indicated as a prognostic factor for various malignancies including non-small cell lung cancer (NSCLC) [13], chronic lymphocytic leukemia [14], and breast cancer [15], etc. However, no study has investigated the association between AFR and EOC until now. This evidence concerns the gene FBL and breast carcinoma.