IDH2 and acute myeloid leukemia: Efficacy for FDA approval was established based on a CR + CR with partial hematologic recovery (CRh) rate of 23% (95% CI of 18–30) and a median remission duration of 8.2 months in 199 adults with R/R AML with the IDH2 mutation per the companion diagnostic test treated with the recommended dose of enasidenib [36].