PTEN and lung adenocarcinoma: Specifically, we observed that the top enriched pathways were HIPPO signaling for bladder, PTEN signaling for breast, iNOS and Interferon signaling for lung adenocarcinoma, Acyl-CoA Hydrolysis for stomach, and DNA Double-Strand Break Repair and Fatty Acid α-oxidation for pancreas, EIF2 signaling for thyroid and GPCR-Mediated Integration for kidney (P < 0.01 for all; Additional file 1: Table S7).