In addition, we also evaluated the associations of APOBEC-mutational signature with the gene expression of other APOBEC3 genes: APOBEC3C, APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H. Our results showed that expressions of these genes were associated with APOBEC-mutational signature varied in distinct cancer types (Additional file 1: Table S2). This evidence concerns the gene APOBEC3F and cancer.