Moreover, SNHG6 silencing significantly inhibited the expression of miR-101-3p in both CRC cell lines (Fig. 2c; P < 0.05), but miR-101-3p knock-down didn’t cause any change in the expression of SNHG6 (Fig. 2d; P > 0.05). Here, SNHG6 is linked to colorectal carcinoma.