Could GAS5 provide similar high-level regulation—influencing dozens of coding genes that together contribute to its tumor-suppressor phenotype—including genes controlling cell proliferation (such as cyclins and cyclin-dependent kinases) or apoptosis (such as the BH3-only member of the BCL2 family (Bim, Bid), caspases or PTE)? The gene discussed is GAS5; the disease is neoplasm.