Natural killer (NK)-cell-derived exosomes carrying the tumor suppressor miR-186 induced cytotoxicity when internalized by MYCN-amplified NB cell lines, through an inhibitory action on MYCN expression, Aurora Kinase A (AURKA), and transforming growth factor (TGF)-β-receptors 1–2 [42]. The gene discussed is AURKA; the disease is neoplasm.