Next, all fibrosarcoma samples obtained following grafting of PTX3-MC17-51 or mock-MC17-51 cells in syngeneic mice or from wild type MC17-51 tumors generated in WT and transgenic TgN(Tie2-hPTX3) mice were evaluated for their neovascular response and immune inflammatory infiltrate by IHC. Here, PTX3 is linked to fibrosarcoma.