For activation of CD94+ killer cells, evident HSP-ligands are full-length ex-HSP70 [10], Hsp70 C-terminal domain, TKD (a 14-mer peptide derived from the N-terminal sequence of Hsp70 TKDNNLLGRFELSG, aa 450–463) [11,97,122,123], mHSP70 expressed on infected red blood cells [11], and tumor-derived HSP-exosomes [73]. Here, KLRD1 is linked to neoplasm.