AFP and cancer: In multivariate Cox models after adjustment for co‐predictors (ie, age, gender, family history of non‐HCC cancer, smoking and drinking habitus, level of education, BMI, etiology of liver disease, presence of cirrhosis, Model for end‐stage liver disease [MELD] score, platelet count, serum AFP levels, BCLC stage, and infiltrative type of tumor), a family history of HCC was independently associated with improved overall survival (adjusted hazard ratios [HRs], 0.89; 95% confidence interval [CI], 0.80 to 0.98, P = .025; Table 2).