MEG3 and cancer: For instance, lncRNA maternally expressed gene 3 (MEG3) has been reported to function as a tumor suppressor in various cancers such as hemangioma (10), osteosarcoma (11), and thyroid carcinoma (12), and it can serve as a ceRNA for miR-9-5p to mediate the progression of esophageal cancer (13) and prostate cancer (14).