The recent discovery that R7BP is a master regulator of itch sensation10 provides hope for the development of novel anti-itch therapeutics that might be effective towards multiple types of itch, especially for chronic itch, such as eczema and neuropathies, for which there are currently few specific and effective drugs whose use is not hampered by undesirable side effects. This evidence concerns the gene RGS7BP and Eczematoid dermatitis.