GATA1 deficiency will lead to abnormal cell apoptosis in the early proliferation and differentiation of erythrocytes, leading to severe anemia and severe thrombocytopenia [35, 36, 39], and GATA1 plays an indispensable role in determining the fate of bone marrow-erythrocytic lineage during embryogenesis [40]. The gene discussed is GATA1; the disease is Thrombocytopenia.