For instance, BM-MSCs from lupus-like mice and patients with systemic lupus erythematosus showed reduced levels of MCP-1, which impaired their capacity to suppress B-cell responses [70], and MCP-1 mRNA expression was decreased in BM-MSCs from patients with newly diagnosed type 1 diabetes [71]. This evidence concerns the gene CCL2 and systemic lupus erythematosus.