Then, in order to confirm the most relevant hub genes, we used correlation analysis in GEPIA, and we detected JUN and VEGFA, JUN and ATF3, and JUN and RHOB are distinctly correlated (P value = 0, R=0.47; P value = 0, R=0.71; P value = 0, R=0.69), which means JUN may be the core gene of HCC (Figures 4(e)–4(g)). This evidence concerns the gene ATF3 and hepatocellular carcinoma.