IL22 and neoplasm: LLC1 tumours showed a downregulation of inflammatory cytokines such as IL-12, IL-5, IL-10 and TNF-α after a cell-based Reovirus vaccine treatment.55 In contrast, we detected a significant induction of predominantly inflammatory cytokines IFN-γ, IL-17a, IL-22, MP-1α, RANTES and IP10.