The Psychiatric Genomic Consortium (PGC) did not find association of case status with rs12467877 (P = 0.076) in their large case-control schizophrenia GWASs4,53, which indicates that the NRXN1 association is pertinent to the intermediate phenotype (THLV volume) and not directly with diagnosis. The gene discussed is NRXN1; the disease is schizophrenia.