Interestingly, forced overexpression of miR-141 in PCa cells suppressed stemness of PCaSCs including growth and proliferation of stem cells, invasion, tumor recurrence, and metastasis via targeting a cohort of prometastatic genes including CD44, EZH2, and Rho GTPases, suggesting that miR-141 may be a viable target for PCa therapy [162]. The gene discussed is CD44; the disease is neoplasm.