In the study by Sixt et al. [98], infection by a cpoS mutant was shown to activate the stimulator of interferon genes (STING), leading to its re-localization from the endoplasmic reticulum (ER) to perinuclear vesicles and to the triggering of a signalling pathway that results in an enhanced interferon (IFN) response [98]. The gene discussed is STING1; the disease is infection.