The results showed that there was significant difference risk of glioma between the GSTP1 Ile105Val Val/Val genotype and Ile carriers among the Han Chinese population (OR=2.035(1.216-3.406); P=0.007) compared with that expected in the overall population (OR=0.902(0.650-1.251); P=0.535), the Caucasian population (OR=0.799(0.504-1.268); P=0.342) and a mixed population (OR=0.756(0.541-1.057); P=0.102) (Figure 2a). The gene discussed is GSTP1; the disease is central nervous system cancer.