28, 30 In a previous study by Mazzio et al, a high throughput screen suggested that galangin could suppress LPS/IFNγ-activated glioma cells 31. In addition, Lei et al reported that galangin could prevent A172 glioma cell invasion by increasing ERK1/2 phosphorylation 32. The gene discussed is MAPK3; the disease is central nervous system cancer.