On the other hand, When MCM6 expression was high, gastric cancer patients with low expression of CDK5RAP3 had a poorer prognosis than did those with high CDK5RAP3 expression, while no significant overall survival difference was observed between the patients with low or high CDK5RAP3 when MCM6 expression was low (P<0.05, Fig. 5D-F). This evidence concerns the gene MCM6 and gastric cancer.