POM121 and metastatic malignant neoplasm in the lymph nodes: Multivariate analysis showed that high POM121 expression (HR, 1.844; 95% CI, 1.321-2.575; P<0.001) was an independent prognostic factor for OS, as well as lymph node metastasis (HR, 1.322; 95% CI, 1.053-1.659; P=0.016) and TNM stage (HR, 1.163; 95% CI, 1.017-1.331; P=0.028) (Table 3).