Comparing the distribution of the intensity scores of all lesions (except for invasive carcinoma which does not stain at all with either anti-CK5 or anti-CK5/6) diagnosed in both the anti-CK5/6 and the anti-CK5 stained populations, suggest strongly that staining with anti-CK5 results in much more strongly (clearer) staining lesions than anti-CK5/6 (Tables 2 and 3). This evidence concerns the gene KRT5 and invasive carcinoma.