To further investigate the phenotype of GLUT1 overexpression in HPV16-positive cervical cancer, we examined the effects of GLUT1 overexpression on tumor immune microenvironment, based on the hypothesis that GLUT1-mediated immune evasion in the HPV16-positive cervical cancer could affect the treatment outcome27,28. This evidence concerns the gene SLC2A1 and cervical carcinoma.