Therefore, to elucidate the effect of the combination of HPV genotypes and tumor metabolism, mediated by GLUT1, on the treatment outcomes and tumor microenvironment in cervical cancer, we analyzed these biomarkers in patients with cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), using The Cancer Genome Atlas (TCGA) database. The gene discussed is SLC2A1; the disease is cervical squamous cell carcinoma.