FASN and cancer: Downregulations of lipogenesis-related genes and enzymes, including fatty acid synthase (FASN)4, 3-hydroxy-3-methylglutaryl-CoA synthase (HMG-CoA synthase)5, and sterol-regulatory-element-binding protein-1c/2 (SREBP-1c/2)6 have been shown to inhibit cancer growths significantly.