Moreover, phospho-ERK and phospho-AKT were detected in human NKTCL samples, with significantly higher levels in patients with the mutant GNAQ T96S genotype than in patients with the wild-type Gαq genotype using two immunohistochemistry scoring methods (Fig. 6e and Supplementary Fig. 7). The gene discussed is AKT1; the disease is extranodal nasal NK/T cell lymphoma.