Although proteins containing cross-reactive peptides recognized by A2/NY-ESO-1157 scFv, such as SLC13A2, TAS2R8, LYPLAL1 as shown in Fig. 7b, are likely to be expressed in normal tissues, their expression level does not appear to be higher than that of NY-ESO-1 expressed by tumor cells, at least on the basis of an in silico search. The gene discussed is LYPLAL1; the disease is neoplasm.