In sum, these results obtained from the TCGA and GTEX databases revealed that in various tumor stages (T stage), Rab1A expression in cholangio carcinoma, pancreatic adenocarcinoma, stomach adenocarcinoma, colon adenocarcinoma, rectum adenocarcinoma and liver hepatocellular carcinoma tissues was higher than paired controls. The gene discussed is RAB1A; the disease is colon adenocarcinoma.