Moreover, analysis of the RNA sequencing data of the SNUH cohort, containing 81 normal thyroid tissues, 25 thyroid adenomas, and 77 PTCs showed that CXCL16 was significantly upregulated in the PTCs compared to the normal thyroid tissues or benign adenomas (P < 0.001, Fig. 1B). The gene discussed is CXCL16; the disease is Thyroid adenoma.