A subset of the GERD genes also have an effect on BE and/or EA, and are therefore possible drug targets for these conditions: among the putative drug targets in Table 4, the peak SNPs in two genes (EPHB1 and CCKBR) show a larger effect (odds ratio) on BE/EA than they do on GERD. The gene discussed is EPHB1; the disease is gastroesophageal reflux disease.