Two further genes (MST1R and CDK2) show a similar effect size for BE/EA as for GERD (although the P-values are only 0.05 < P < 0.1 due to the smaller sample size for BE/EA), whilst three (PDE4B, DYPD, and LAMA2) show no association with BE/EA. This evidence concerns the gene PDE4B and gastroesophageal reflux disease.